Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,486
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1,500
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results
1,486
Tocris Bioscience™ VH 032 amide-alkylC5-amine
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VHL ligand with alkyl linker and terminal amine for onward chemistry
1,487
Tocris Bioscience™ SC 144 hydrochloride
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gp130 inhibitor; blocks cytokine-triggered gp130 signaling
| Inhibitors | SC 144 hydrochloride |
|---|---|
| Product Type | SC 144 hydrochloride |
| Molecular Weight (g/mol) | 358.76 |
| Purity | >99% |
1,488
Tocris Bioscience™ Telenzepine dihydrochloride
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CAS: 147416-96-4 Molecular Formula: C19H24Cl2N4O2S
| CAS | 147416-96-4 |
|---|---|
| Molecular Formula | C19H24Cl2N4O2S |
1,489
| Shipping Condition | No special requirements |
|---|---|
| CAS | 64461-82-1 |
| Color | White to Yellow to Light-brown |
| Solubility | Soluble aqueous solution |
| Purity | ≥97.5% |
| Physical Form | Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Tizanidine hydrochloride |
| Recommended Storage | Normal conditions |
| Synonym | 5-Chloro-4-[(4,5-dihydro-1 H-imidazol-2-yl)amino]-2,1,3-benzothiadiazole hydrochloride |
| Molecular Formula | C9 H8 Cl N5 S . H Cl |
| Melting Point | 280°C |
| Product Line | Life science |
1,490
Tocris Bioscience™ CGP 60474
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Potent cdk inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 164658-13-3 |
| Purity | >98% |
| Chemical Name or Material | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H18ClN5O |
| Formula Weight | 355.82 |
1,491
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-PEG2-amine
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Thalidomide-PEG2-ethylamine
1,492
Tocris Bioscience™ Z-Guggulsterone
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Broad spectrum steroid receptor ligand. More active isomer of guggulsterone (Cat. No. 2013)
| Inhibitors | Z-Guggulsterone |
|---|---|
| Product Type | Z-Guggulsterone |
| Molecular Weight (g/mol) | 312.45 |
| Purity | >98% |
1,493
Tocris Bioscience™ TBI
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Fluorogenic ligand for Broccoli RNA aptamer
1,494
Tocris Bioscience™ DMSO, Cell Cryopreserve Grade
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Intracellular cryoprotective agent
1,495
Tocris Bioscience™ NIR Dye s775z, NHS
Bright and photostable non-aggregating near-IR cyanine dye. Reactive group: NHS ester
1,496
Tocris Bioscience™ THPTA
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Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
1,497
Tocris Bioscience™ Janelia Fluor™ 635, Tetrazine
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Red dye (Reactive group: tetrazine). Application: confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging
1,498
Tocris Bioscience™ Rilpivirine
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Non-nucleoside reverse transcriptase inhibitor
| Target | RNA/DNA Polymerase Inhibitors |
|---|---|
| CAS | 500287-72-9 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[[4-[[4-[(1 E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H18N6 |
1,499
Tocris Bioscience™ PB 28 dihydrochloride
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High affinity σ2 agonist
| CAS | 172907-03-8 |
|---|---|
| Solubility | Soluble to 20mM with gentle warming in water |
| Chemical Name or Material | 1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine dihydrochloride |
| Recommended Storage | Desiccate at +4°C |
| Molecular Formula | C24H38N2O.2HCl |
| Formula Weight | Observed MW: 443.5 |
| Assay Percent Range | >99% |
1,500
Tocris Bioscience™ TASP 0433864
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective mGlu2 receptor positive allosteric modulator
| CAS | 1431980-60-7 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | White |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | (2S)-2-[[4-(1,1-Dimethylethyl)phenoxy]methyl]-2,3-dihydro-5-methylimidazo[2,1-b]oxazole-6-carboxamide |
| Recommended Storage | Store at 4°C |
| Synonym | mGlu2 receptor positive allosteric modulator |
| Molecular Formula | C18H23N3O3 |
| Formula Weight | 329.39 |